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RMRC No. RMRC13303 Order
Strain/Stock Designation C57BL/6-Smad4tm1a(GEMMS)Narl/Narl
Status
SP| (Cryopreserved or freeze-dried sperm)
Availability Level4
Pricing Industry:30,300NTD Academia: 30,300NTD NSTC: 21,210NTD
Last Update Date 2017/9/1
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species laboratory mouse
Strain Type COI (coisogenic strain),MSR (mutant strain)
Mutant Type TM (Target Mutation)
Other Names
Background Strain C57BL/6
Strain Description
1.  Knockout first mice 
2.  The BAC-based targeting construct was electroporated into C57BL/6J embryonic stem (ES) cells
3.  Exon ENSMUSE00000324382 to ENSMUSE00000337424were replaced with Smad4 cDNA and frt-flanked neomycin resistant gene.
4.  Smad4cDNA and neomycin resistant gene are loxP-flanked followed by RFP.
Depositor
Genetic engineered murine model services (GEMMS) / 基因改造疾病模式鼠核心設施
Email bujiii@nlac.narl.org.tw
Allele Symbol Smad4tm1a(GEMMS)Narl
Allele Name SMAD family member 4, Target mutation 1a, National Applied Research Laboratories
Allele Description
Strain of Origin C57BL/6
Gene Symbol Smad4
Gene Name SMAD family member 4
Chromosome 18
Genotyping Method Download            
Genotyping NLAC            
Research Application
Apoptosis Cancer
Internal/ Organ Metabolism
Construction Technologies
Cre-lox system FLP-FRT system
Animal Health Reports
Colony Maintenance
Breeding & Husbandry
Colony Maintenance
Mating System
hetero/hemi x wild type
References No

Specific Terms of Use
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果,不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時,應揭露並致謝本材料係由GEMMS-NLAC所提供
Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge GEMMS-NLAC
Construct Map
 
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