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RMRC No. RMRC13003 Order
Strain/Stock Designation B6;Cg-Tg(SMN2)Hung Smn1tm1Hung/Narl
Status
EM| (Cryopreserved Embryos)
Availability Level4
Pricing (Embryos) 　Industry：11,105NTD　Academia: 7,775NTD　NSTC: 5,415NTD
(Cryo Recovery) 　Industry：20,815NTD　Academia: 13,880NTD　NSTC: 13,880NTD
Last Update Date 2016/5/26
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species ： laboratory mouse
Strain Type ： MSK (mutant stock)
Mutant Type ： TM (Target Mutation)
Other Names ：
Background Strain ： C57BL/6
Strain Description ：
1.  Human SMA model
2.  Smn1-/- is embryonic lethal
3.  Three expression forms of Smn-/-SMN2+:
(1) died within D7，
(2) died at around D12，
(3) mice could grow to adult, but the tail and the ears would atrophy gradually.
Depositor ：
Li, Hung / 李鴻
Email ：
Allele Symbol ： Smn1tm1Hung
Allele Name ： survival motor neuron 1, targeted mutation 1, Hung Li
Allele Description ：
Allele Symbol ： Tg(SMN2)Hung
Allele Name ： Transgenic insertion, Li, Hung
Strain of Origin ： 129P2/OlaHsd*FVB
Gene Symbol ： Smn1
Gene Name ： survival motor neuron 1
Chromosome ： 13 (+ strand)
Genotyping Method ： Download            
Genotyping NLAC ：            
Research Application ：
Immunology and Inflammation Cell and Developmental Biology
Neurobiology Research Pharmacology and Toxicology
Construction Technologies ： No
Animal Health Reports ：
Colony Maintenance
Breeding & Husbandry 		：
Colony Maintenance
Mating System 		： hetero/hemi x wild type
References ： PubMed ID: 10615130

Specific Terms of Use ：
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： A mouse model for spinal muscular atrophy. Hsieh-Li HM, et al., Nat Genet. 2000 Jane;24(1):66-70
Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： A mouse model for spinal muscular atrophy. Hsieh-Li HM, et al., Nat Genet. 2000 Jane;24(1):66-70
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Dr. Hung Li, Academia Sinica所提供
Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Dr. Hung Li, Academia Sinica
分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時，應附上寄存人簽名之授權分讓同意書作為附件；NLAC- RMRC 在取得寄存人書面同意後，始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email:
Construct Map ：
 
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